Name: Berberine powder
Brand: Joyous Pellets Supplement raw materials, cosmetic ingredients, weight
Availability: InStock
Rating: 5 (1 reviews)

Berberine is a quaternary ammonium alkaloid isolated from the traditional Chinese medicine Coptis chinensis and is the main active antibacterial ingredient of Coptis chinensis. It has a wide antibacterial spectrum. Berberine has antibacterial effects both in vitro and in vivo. It also plays a very important role in reducing and regulating blood lipids and treating diabetes.

Product Name

Berberine

Appearance

Yellow powder

Specification

98%

CAS No

2086-83-1

Molecular Formula

C20H18NO4+

Package

25kg cardboard drum

GET A QUOTE

Add to Quote List Просмотрите список

Desciption

Product information
What is Berberine powder?
Berberine is a quaternary ammonium alkaloid isolated from the traditional Chinese medicine Coptis chinensis, which has been used for a long time in China. It is the main active antibacterial ingredient of Coptis chinensis. It generally appears as yellow needle-like crystals and tastes bitter. It is widely distributed in the plant kingdom and can be extracted from Coptidis chinensis, Phellodendron cypress, and three needles. Berberine hydrochloride is commonly used. Berberine can fight against pathogenic microorganisms and has inhibitory effects on a variety of bacteria such as Shigella dysenteriae, Mycobacterium tuberculosis, Pneumococcus, Typhoid bacilli and Diphtheria bacilli. Among them, it has the strongest effect on Shigella dysenteriae and is often used to treat bacterial infections. Gastroenteritis, dysentery and other digestive tract diseases. It is mainly used clinically to treat bacterial dysentery and gastroenteritis, and it has no drug resistance or side effects.
Joyous Berberine powder specification

Terms	Standard	Terms	Standard
Product Name	Berberine	Appearance	Yellow powder
Assay	98%	Loss on Drying	≤2%
Total Heavy Metals	≤10 ppm	Ash	≤2%
As	≤0.5ppm	Total Plate Count	≤750 cfu/g
Pb	≤0.5ppm	Yeast and Mold	≤100 cfu/g
Cd	≤0.5ppm	Coliforms	Negative
Hg	≤0.1ppm	E.Coli	Negative
Packing	Pack in 25kgs paper-drums, inner by double plastic bag	Shelf life	24 months under the above condition, and in its original package

What is the function of Berberine?
1. Broad spectrum antibacterial
Berberine has antibacterial effects on a variety of Gram-positive and negative bacteria in vitro, including hemolytic Streptococcus, Staphylococcus aureus, and Vibrio cholerae. Meningococci, Shigella dysenteriae, Typhoid bacilli, Diphtheria bacilli, etc. have strong inhibitory effects. They are bacteriostatic at low concentrations and sterilizing at high concentrations. It also has certain inhibitory effects on influenza viruses, amoeba, leptospira, and certain skin fungi. In vitro experiments have confirmed that berberine can enhance the phagocytic ability of leukocytes and liver reticuloendothelial system. Shigella dysenteriae, hemolytic Streptococcus, Staphylococcus aureus, etc. are easily resistant to this product. There is no cross-resistance between this product and penicillin and streptomycin. However, oral absorption is poor. After injection, it quickly enters various organs and tissues, and the blood concentration is maintained for a short time. The blood concentration after intramuscular injection is lower than the minimum inhibitory concentration. The drug is widely distributed, mostly in the heart, bones, lungs and liver. The retention time in tissues is short, and only a trace amount remains after 24 hours. Most of the drugs are metabolized and eliminated in the body, and only less than 5% of the administered dose is excreted in the original form within 48 hours. Joyous believes that berberine can reduce the number of pili on the surface of bacteria, preventing bacteria from attaching to human cells, and has a therapeutic effect. Berberine also has an effect on Helicobacter and can alleviate gastritis, gastric and duodenal ulcers.
2. Reduce and regulate blood lipids
Berberine lowers blood lipids at the post-transcriptional level of the gene by acting on the 3'UTR region to stabilize the mRNA (messenger ribonucleic acid) of the low-density lipoprotein receptor. It has the same mechanism of action as currently used statin blood-lipid-lowering drugs. different. This theoretically provides new molecular targets for the search for new blood lipid-lowering drugs. Clinical studies have shown that oral administration of berberine (1 gram per day for three months) can reduce cholesterol, low-density lipoprotein, and triglycerides in patients with hyperlipidemia by 20% to 35%. This result was further confirmed by the golden hamster model of hyperlipidemia. Confirmed by animal experiments. The backbone of the research team, Dr. Wei Jing of Nanjing First Hospital, and Dr. Liu Jingwen, a Chinese scientist from the Parralto Veterans Hospital in California, USA, both said that berberine may become a substitute for statins and is expected to be used in conjunction with statins. Drug combinations to treat cardiovascular disease. Berberine can significantly upregulate the expression of low-density lipoprotein receptor (LDLR) in hepatocytes in vitro. Further studies have shown that berberine works at the post-transcriptional level by activating the extracellular signal-regulated kinase of cells, which is completely different from the mechanism of statin cholesterol-lowering drugs currently commonly used in clinical practice. Clinical application shows that berberine has good efficacy in treating patients with hyperlipidemia
3. Treat diabetes
According to a report in the August issue of "Diabetes" magazine, results of studies on mice indicate that berberine extracted from plants may reduce body weight and improve glucose tolerance by stimulating adenosine monophosphate (AMP)-activated protein kinase activity. Dr. Jae B. Kim of Seoul National University in South Korea and his colleagues wrote that preliminary work shows that berberine, one of the important components of Oriental Materia Medica, has a positive effect on obesity and diabetes. To investigate further, the researchers gave berberine to obese and diabetic mice. As a result, the mice lost weight and significantly improved their glucose tolerance without changing their diet. In addition, berberine reduced body weight and plasma triglycerides and improved insulin activity in Wistar rats fed a high-fat diet. Berberine activates AMP kinase in adipocytes and muscle cells, inducing different metabolic effects related to its activity.
4. Can be used by people with liver dysfunction
When berberine was used to treat patients with hyperlipidemia, it was found that for patients with liver dysfunction, berberine is still safe and does not have the adverse reactions of statins. The results of this study have been confirmed by many research units and hospitals in Europe and the United States, and have been accepted and praised by patients at home and abroad. This also makes berberine a promising drug for lowering blood lipids.
Package and delivery

Delivery
1-80kg	80-300kg	More than 300kg
More suitable for express transportation, door-to-door	More suitable for air transportation,airport-to-airport	More suitable for ocean transportation,port-to-port
7-10 days for delivery time	3-4 days for delivery time	20-40 days for delivery time

What service we can provide
Joyous Health provides Berberine powder OEM services. We can customize formulas for customers, private labels, capsules, tablets, soft capsules and sachets, low MOQ, which is suitable for direct sales by brands. Our OEM product shipping channels are stable and delivery times are fast and worthy of customers' trust, we have served more than 300 brands.

Joyous Health Factory information and certifications
Xi'an Joyous Health Biotechnology Co., Ltd. was established in 2011. Over the past 12 years, Joyous Health has obtained ISO 9001, FDA, ISO 22000, and GMP certifications.
Joyous Health has an advanced laboratory to control quality, so that each batch of products undergoes strict testing, and has professional R&D personnel to provide customized product services.
For more details please click here

Where to buy Berberine powder?
We offer the best Berberine powder at the most competitive price.Berberine Powder bulk and wholesale powder have been 3rd lab-tested and verified for both product purity and identity.
We also provide Berberine powder in bulk order or wholesale according to client needs. Just submit the requirements in the bottom form, we will reply soon!

Contacts: Faith Feng
Email:faith@joyouspellets.com
Tel and Whatsapp:+86 17391747738

REQUEST MORE DETAILS

Please fill out the form below and click the button to request more information about

We provide high-quality products and services, as well as customized pellets. We are a professional ingredient supplier and solution provider.

Contact: Xi'an international enterprise center B building, Fengcheng 4 road, Xi'an City, Shaanxi province, China; info@joyouspellets.com; +86 17391747738

Follow Us

Lates News: Don't miss our news subscription, please fill in the form below.

Leave Message

FirstName*

LastName*

Email*

Tel No.

Message

Мы используем файлы cookie, чтобы улучшить вашу работу в Интернете. Продолжая просматривать этот сайт, вы соглашаетесь на использование нами файлов cookie.